Infrared surface plasmon and waveguide modes spectroscopy for live cell biosensing
Par Victor Yashunsky, Laboratoire Physico-Chimie Curie, Institut Curie, Paris
Mardi 24 Mai, 14h, Salle des séminaires, 3ème étage, Batiment A4
In addition to surface plasmon resonance in infrared range, we discovered a novel bio-optical phenomenon of waveguide modes propagating inside living cells. We found that such waveguide modes can be observed in intact epithelial cell monolayers and thus can provide complimentary information about cell connectivity and cell layer thickness.
Combined together surface plasmon and waveguide modes enable precise structural analysis of cell populations in real-time and in label-free manner. This has great importance for understanding the collective behavior of cells in the context of tissues and organs.
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